{"product_id":"l-arginine-sustained-immediate-release","title":"L-Arginine - Sustained + Immediate Release","description":"\u003cp\u003e\u003cstrong\u003eDescription:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Doctor's Best Sustained Plus Immediate Release Arginine?\u003c\/strong\u003e\u003cbr\u003eDoctor's Best Sustained Plus Immediate Release Arginine promotes a healthy cardiovascular system, enhances healthy circulation and supports heart function. L-arginine has been shown to support the cardiovascular system, through its conversion to nitric oxide. Research suggests L-arginine supplementation may also have positive benefits on athletic performance. Two tablets of Doctor's Best Sustained Plus Immediate Release Arginine delivers 1000mg L-arginine in a bilayer tablet, with two tablets providing 500 mg of sustained release and 500 mg of immediate release L-arginine. This technology allows for enhanced blood levels of L-Arginine for a continuous period of up to 8 hours.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does it work?\u003c\/strong\u003e\u003cbr\u003eOral L-arginine supplementation has been shown in clinical studies to support various aspects of cardiovascular health. A randomized double-blind placebo-controlled trial found that six weeks of L-arginine supplementation enhanced circulation and supported healthy heart function compared to placebo. The L-arginine effect was due to its role in NO production. Other clinical trials have shown that oral L-arginine supplementation contributes to enhanced exercise tolerance because of its ability to enhance cardiac circulation and vasodilation of blood vessels. L-arginine enrichment of the diet in healthy individuals was shown to support blood pressure already in the normal range. The overall results of these and other clinical trials showed that long-term administration of this amino acid significantly enhanced endothelial function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy take Sustained and Immediate Release Arginine?\u003c\/strong\u003e\u003cbr\u003eThe normal aging process in humans has been found to be associated with progressive changes in endothelial function (cells that line the inner surfaces of blood vessels). Research suggests that a major reason for these common changes associated with aging is reduced production or bioavailability of nitric oxide (NO) in vessels and tissues. L-arginine is a substrate for the enzyme nitric oxide synthase, required for the production of nitric oxide in the body. Nitric oxide is a substance critical for the maintenance of normal vascular function. NO mediates a number of physiological effects on the cardiovascular system, including supporting healthy endothelial function, enhancing cardiovascular health and displaying potent antioxidant properties against free radicals.\u003c\/p\u003e\n\u003cp data-start=\"0\" data-end=\"20\" class=\"PDq2pG_selectionAnchorContainer\"\u003e\u003cstrong data-start=\"0\" data-end=\"20\"\u003eSupplement Facts\u003c\/strong\u003e\u003cspan aria-hidden=\"true\" class=\"PDq2pG_selectionAnchor\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-start=\"22\" data-end=\"49\"\u003eServing Size: 2 Tablets\u003c\/p\u003e\n\u003cp data-start=\"51\" data-end=\"81\"\u003eServings Per Container: 60\u003c\/p\u003e\n\u003cdiv class=\"TyagGW_tableContainer\"\u003e\n\u003cdiv class=\"group TyagGW_tableWrapper flex flex-col-reverse w-fit\" tabindex=\"-1\"\u003e\n\u003ctable data-start=\"83\" data-end=\"284\" class=\"w-fit min-w-(--thread-content-width)\"\u003e\n\u003cthead data-start=\"83\" data-end=\"122\"\u003e\n\u003ctr data-start=\"83\" data-end=\"122\"\u003e\n\u003cth data-start=\"83\" data-end=\"108\" data-col-size=\"lg\" class=\"last:pe-10\"\u003e\u003cstrong data-start=\"85\" data-end=\"107\"\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth data-start=\"108\" data-end=\"122\" data-col-size=\"sm\" class=\"last:pe-10\"\u003e\u003cstrong data-start=\"110\" data-end=\"120\"\u003eAmount\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody data-start=\"164\" data-end=\"284\"\u003e\n\u003ctr data-start=\"164\" data-end=\"284\"\u003e\n\u003ctd data-start=\"164\" data-end=\"273\" data-col-size=\"lg\"\u003eL-Arginine (as 500 mg immediate release and 500 mg sustained release from L-Arginine alpha-Keto-Glutarate)\u003c\/td\u003e\n\u003ctd data-col-size=\"sm\" data-start=\"273\" data-end=\"284\"\u003e1000 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp data-start=\"286\" data-end=\"460\"\u003e\u003cstrong\u003eL-Arginine Other Ingredients: \u003c\/strong\u003e\u003cbr\u003eMicrocrystalline cellulose, stearic acid, silicon dioxide, magnesium stearate (vegetable source), croscarmellose sodium, hypromellose (coating).\u003c\/p\u003e\n\u003cp data-start=\"462\" data-end=\"591\"\u003e\u003cstrong\u003eL-Arginine Recommended Use: Adult: \u003c\/strong\u003e\u003cbr\u003eTake 2 tablets daily, away from food, or as recommended by a nutritionally-informed physician.\u003c\/p\u003e\n\u003cp data-start=\"593\" data-end=\"1065\" data-is-last-node=\"\" data-is-only-node=\"\"\u003e\u003cstrong\u003eWarnings: \u003c\/strong\u003e\u003cbr\u003eConsult your physician before using this product if you are pregnant, lactating, have a medical condition, on prescription medications, or other supplements that may lower blood pressure while taking in concomitant with this product. Not for use by individuals under the age of 18 years. Keep out of reach of children. Non-GMO, Gluten Free, Soy Free, Vegan. This product is not intended to diagnose, treat, cure or prevent any disease. Store in a cool dry place.\u003c\/p\u003e\n\u003cp data-start=\"593\" data-end=\"1065\" data-is-last-node=\"\" data-is-only-node=\"\"\u003e\u003cspan\u003e\u003cstrong\u003eExpires:\u003c\/strong\u003e 2027-09-30\u003c\/span\u003e\u003c\/p\u003e","brand":"Doctor's Best","offers":[{"title":"Default Title","offer_id":54779962589525,"sku":"P7089","price":27.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1058\/0521\/8133\/files\/image_2026-03-09_69aeaad1e1985.jpg?v=1787948229","url":"https:\/\/amvibe.co.uk\/products\/l-arginine-sustained-immediate-release","provider":"AM Vibe","version":"1.0","type":"link"}